Materialistic characterization, thermal properties, and cytocompatibility investigations on acrylic acid-functionalized nSiO2-reinforced PEEK polymeric nanocomposite

Polyether ether ketone (PEEK) is a biocompatible alternative to metallic biomaterials because of its unique properties and biocompatibility. Its bioinert nature may lead implant failure from inadequate osseointegration. Therefore, this research aims develop the nSiO2 ceramic particle-reinforced PEEK (nSiO2@PEEK) polymer nanocomposite. The particle size nanoparticles was measured as 43.6 nm using analyzer (PSA). morphology fabricated composite analyzed FESEM. structural characteristic nSiO2@PEEK investigated XRD FTIR. Thermal stability examined TGA thermograms DSC curves. Minimum toxic level (grade: slight, 1–20%) observed by in vitro cytotoxicity assessment direct indirect methods. Excellent cell viability found 83.6% through MTT assay. MG-63 adhesion study conducted subsequently excellent growth were monitored SEM analysis. This investigation nanocomposite be biocompatible. It promising biomaterial for medical implants.